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Genetics 466 Course Outline - Fall 2006
2:25 MWF 125 Biochemistry
Prof. John Doebley
Prof. Patrick Masson
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| Date |
Lecture Topic |
Readings |
Suggested Problems |
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| Part 1. |
Genes, Chromosomes and Linkage |
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| Sept 6 |
1. Mendel and The Study of Inheritance |
1:1-15; 3:42-49 |
3: Q1, 2, 4-10 |
Daily |
Lecture |
| Sept 8 |
2. Probability for Genetic Events |
3:49-51 (handout) |
3: Q17, 22, 23 |
Daily |
Lecture |
| Sept 11 |
3. Probability for Repeated Trials |
3:54-59 |
3: Q15-16, 18-21, 27 |
Daily |
Lecture |
| Sept 13 |
4. Testing Genetic Hypotheses |
3:51-53 |
3: Q3, 11-14 |
Daily |
Lecture |
| Sept 15 |
5. Extensions to Mendelism |
4:65-81 |
4: Q2, 3, 6, 7-12, 19-20. |
Daily |
Lecture |
| Sept 18 |
6. Cell Cycle, Mitosis and Meiosis |
2:17-33, 40 |
2: BX2-4, Q9-15 |
Daily |
Lecture |
| Sept 20 |
7. Chromosomes, Sex and Mendel |
5:85-103 |
5: Q2-11, 14-21, 24. |
Daily |
Lecture |
| Sept 22 |
8. Chromosome Number |
6:106-120 |
6: Q1, 3-8, 11, 12 |
Daily |
Lecture |
| Sept 25 |
9. Chromosome Rearrangements |
6:129-155 |
6: Q14-16, 18, 22-26 |
Daily |
Lecture |
| Sept 27 |
10. Linkage and Mapping I |
7:129-144 (handout) |
7: Q1, 3, 6, 7-17 |
Daily |
Lecture |
| Sept 29 |
11. Linkage and Mapping II |
8:190-199 |
7: Q18-19, 21-26, 29-32 |
Daily |
Lecture |
| Oct 2 |
12. Linkage and Mapping III |
7:144-146, (handout) |
8: Q23, 25, 26, 27, 29 |
Daily |
Lecture |
| Part 2. |
Phage and Bacterial Genetics |
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| Oct 4 |
13. Phage Genetics |
7:162-173; 40-406 |
14: 15, 31, 32 |
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Lecture |
| Oct. 6 |
14. Bacterial Genetics I |
8: 173-178 |
8: 9, 12, 16, 18, 19 |
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Lecture |
| Oct. 9 |
15. Bacterial Genetics II |
8: 178-190 |
8: 20, 21, 22 |
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| Part 3. |
Molecular Biology of the Gene |
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| Oct. 11. |
16. Structure of DNA and Chromosomes |
9: 204-237 |
9: 1, 5, 11, 15 |
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Lecture |
| Oct 12 |
Exam I Thursday Evening 7:15 till 9:15 - 125 Ag Hall (Lectures 1 to 15) |
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(Practice Exam) |
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| Oct. 13 |
17. Replication of DNA |
10: 241-273 |
10: 1, 3, 4, 9, 15, 21, 26 |
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Lecture |
| Oct. 16 |
18. Transcription in Bacteria |
11: 279-291 |
11: 2, 3, 16, 31 |
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Lecture |
| Oct. 18 |
19. Transcription in Eukaryotes |
11: 291-307 |
11: 7-11, 13,19, 27, 38 |
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Lecture |
| Oct. 20 |
20. Translation and the Genetic Code |
12: 311-338 |
12: 1, 4, 6, 14, 18, 20, 32 |
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Lecture |
| Oct. 23 |
21. Mutations |
13: 342-463 |
13: 1, 4, 8, 13, 26, 29, 31 |
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Lecture |
| Oct. 25 |
22. Transposable Elements |
18: 524-546 |
18: 1, 6, 13, 17, 20, 22 |
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| Oct. 27 |
23. DNA Repair and Recombination |
13: 363-374 |
Hand-out |
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Lecture |
| Oct 30 |
24. Techniques in Gene Cloning and Analysis |
15: 417-447 |
15: 2, 4, 7, 10, 15, 16, 19, 22, 27-29 |
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Lecture |
| Nov 1 |
25. Applications of Genetic Engineering |
17: 492-515 |
17: 5, 7, 8, 10, 12, 17-19 |
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Lecture |
| Nov 3 |
26. Genomics and Proteomics |
16: 453-487 |
16: 1, 5, 10, 17, 18, 23 |
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LectureA LectureB |
| Part 4. |
Gene Expression and Development |
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| Nov 6 |
27. Gene Expression in Bacteria I |
20: 569-587 |
20: 2, 3, 5, 6, 8, 11, 18, 19, 22 |
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Lecture |
| Nov 8 |
28. Gene Expression in Bacteria II |
20: 587-595 |
20: 23, 25, 27-30 |
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| Nov 10 |
29. Gene Expression in Eukaryotes I |
21: 599-622 |
21: 6, 8, 14, 17, 21 |
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Lecture |
| Nov 13 |
30. Gene Expression in Eukaryotes II |
17: 515-517 |
Hand-out |
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18: 612-628 |
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| Nov 14 |
Exam II Tuesday Evening 7:15 till 9:15 - 125 Ag Hall (Lectures 16 to 28) |
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(Practice Exam) |
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| Nov 15 |
31. Gene Expression in Eukaryotes III |
22: 638-644 |
22:10, 11, 13; 23:18, 19 |
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Lecture |
| |
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23: 663-683 |
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| Nov 17 |
32. Examples in Animal Development |
22: 632-638; 644-660 |
22: 1, 4, 20-28 |
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Lecture |
| Nov 20 |
33. Genetic Basis of Cancer |
24: 686-706 |
24: 1, 8, 10, 11, 12, 18, 21, 26 |
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Lecture |
| Part 5. |
Population and Quantitative Genetics |
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| Nov 22 |
34. The Inheritance of Complex Traits |
25: 709-722 (handout) |
25: Q1, 4-8 (excel file) |
Daily |
Lecture |
| Nov 27 |
35. Nature versus Nurture |
25: 728-733 (handout) |
25: Q9, 11, 13-19 |
Daily |
Lecture |
| Nov 29 |
36. Genetics of Plant and Animal Breeding |
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- |
Daily |
Lecture |
| Dec 1 |
37. Hardy-Weinberg & The Gene Pool Concept |
26 :737-743,754-755 |
26: Q1-12 |
Daily |
Lecture |
| Dec 4 |
38. Inbreeding |
25: 722-728 |
25: Q20-24 |
Daily |
Lecture |
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17:504-506 |
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| Dec 6 |
39. Genetic Drift |
26: 747-750 |
26: Q15-18, 24-26 |
Daily |
Lecture |
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27: 769-779 |
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| Dec 8 |
40. Natural Selection |
26: 743-744 |
26: 19-22, 29-30 |
Daily |
Lecture |
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27: 760-764 |
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| Dec 11 |
41. Genomes and Evolution |
16: 453-487 |
16: 17, 18, 23, 25 |
Daily |
Lecture |
| Dec 13 |
42. Model Organisms |
2: 33-39 |
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Daily |
Lecture |
| Dec 14 |
Exam III Thursday Evening 7:15 till 9:15 - 125 Ag Hall (Lectures 29 to 42) |
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(Practice Exam) |
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| Dec 15 |
43. Overview |
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| Dec 22 |
Exam IV Friday Evening 5:05 till 7:05 - 125 Ag Hall (covers the whole course) |
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