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Genetics 466 Course Outline - Fall 2006
2:25 MWF 125 Biochemistry

Prof. John Doebley
Prof. Patrick Masson

 

 

 
Date Lecture Topic Readings Suggested Problems    
Part 1. Genes, Chromosomes and Linkage        
Sept 6 1. Mendel and The Study of Inheritance 1:1-15; 3:42-49 3: Q1, 2, 4-10 Daily Lecture
Sept 8 2. Probability for Genetic Events 3:49-51 (handout) 3: Q17, 22, 23 Daily Lecture
Sept 11 3. Probability for Repeated Trials 3:54-59 3: Q15-16, 18-21, 27 Daily Lecture
Sept 13 4. Testing Genetic Hypotheses 3:51-53 3: Q3, 11-14 Daily Lecture
Sept 15 5. Extensions to Mendelism 4:65-81 4: Q2, 3, 6, 7-12, 19-20. Daily Lecture
Sept 18 6. Cell Cycle, Mitosis and Meiosis 2:17-33, 40 2: BX2-4, Q9-15 Daily Lecture
Sept 20 7. Chromosomes, Sex and Mendel 5:85-103 5: Q2-11, 14-21, 24. Daily Lecture
Sept 22 8. Chromosome Number 6:106-120 6: Q1, 3-8, 11, 12 Daily Lecture
Sept 25 9. Chromosome Rearrangements 6:129-155 6: Q14-16, 18, 22-26 Daily Lecture
Sept 27 10. Linkage and Mapping I 7:129-144 (handout) 7: Q1, 3, 6, 7-17 Daily Lecture
Sept 29 11. Linkage and Mapping II 8:190-199 7: Q18-19, 21-26, 29-32 Daily Lecture
Oct 2 12. Linkage and Mapping III 7:144-146, (handout) 8: Q23, 25, 26, 27, 29 Daily Lecture
Part 2. Phage and Bacterial Genetics        
Oct 4 13. Phage Genetics 7:162-173; 40-406 14: 15, 31, 32   Lecture
Oct. 6 14. Bacterial Genetics I 8: 173-178 8: 9, 12, 16, 18, 19   Lecture
Oct. 9 15. Bacterial Genetics II 8: 178-190 8: 20, 21, 22    
Part 3. Molecular Biology of the Gene        
Oct. 11. 16. Structure of DNA and Chromosomes 9: 204-237 9: 1, 5, 11, 15   Lecture
Oct 12 Exam I Thursday Evening 7:15 till 9:15 - 125 Ag Hall (Lectures 1 to 15)   (Practice Exam)    
Oct. 13 17. Replication of DNA 10: 241-273 10: 1, 3, 4, 9, 15, 21, 26   Lecture
Oct. 16 18. Transcription in Bacteria 11: 279-291 11: 2, 3, 16, 31   Lecture
Oct. 18 19. Transcription in Eukaryotes 11: 291-307 11: 7-11, 13,19, 27, 38   Lecture
Oct. 20 20. Translation and the Genetic Code 12: 311-338 12: 1, 4, 6, 14, 18, 20, 32   Lecture
Oct. 23 21. Mutations 13: 342-463 13: 1, 4, 8, 13, 26, 29, 31   Lecture
Oct. 25 22. Transposable Elements 18: 524-546 18: 1, 6, 13, 17, 20, 22    
Oct. 27 23. DNA Repair and Recombination 13: 363-374 Hand-out   Lecture
Oct 30 24. Techniques in Gene Cloning and Analysis 15: 417-447 15: 2, 4, 7, 10, 15, 16, 19, 22, 27-29   Lecture
Nov 1 25. Applications of Genetic Engineering 17: 492-515 17: 5, 7, 8, 10, 12, 17-19   Lecture
Nov 3 26. Genomics and Proteomics 16: 453-487 16: 1, 5, 10, 17, 18, 23   LectureA LectureB
Part 4. Gene Expression and Development        
Nov 6 27. Gene Expression in Bacteria I 20: 569-587 20: 2, 3, 5, 6, 8, 11, 18, 19, 22   Lecture
Nov 8 28. Gene Expression in Bacteria II 20: 587-595 20: 23, 25, 27-30    
Nov 10 29. Gene Expression in Eukaryotes I 21: 599-622 21: 6, 8, 14, 17, 21   Lecture
Nov 13 30. Gene Expression in Eukaryotes II 17: 515-517 Hand-out    
    18: 612-628      
Nov 14 Exam II Tuesday Evening 7:15 till 9:15 - 125 Ag Hall (Lectures 16 to 28)   (Practice Exam)    
Nov 15 31. Gene Expression in Eukaryotes III 22: 638-644 22:10, 11, 13; 23:18, 19   Lecture
    23: 663-683      
Nov 17 32. Examples in Animal Development 22: 632-638; 644-660 22: 1, 4, 20-28   Lecture
Nov 20 33. Genetic Basis of Cancer 24: 686-706 24: 1, 8, 10, 11, 12, 18, 21, 26   Lecture
Part 5. Population and Quantitative Genetics        
Nov 22 34. The Inheritance of Complex Traits 25: 709-722 (handout) 25: Q1, 4-8 (excel file) Daily Lecture
Nov 27 35. Nature versus Nurture 25: 728-733 (handout) 25: Q9, 11, 13-19 Daily Lecture
Nov 29 36. Genetics of Plant and Animal Breeding - - Daily Lecture
Dec 1 37. Hardy-Weinberg & The Gene Pool Concept 26 :737-743,754-755 26: Q1-12 Daily Lecture
Dec 4 38. Inbreeding 25: 722-728 25: Q20-24 Daily Lecture
    17:504-506      
Dec 6 39. Genetic Drift 26: 747-750 26: Q15-18, 24-26 Daily Lecture
    27: 769-779      
Dec 8 40. Natural Selection 26: 743-744 26: 19-22, 29-30 Daily Lecture
    27: 760-764      
Dec 11 41. Genomes and Evolution 16: 453-487 16: 17, 18, 23, 25 Daily Lecture
Dec 13 42. Model Organisms 2: 33-39 - Daily Lecture
Dec 14 Exam III Thursday Evening 7:15 till 9:15 - 125 Ag Hall (Lectures 29 to 42)   (Practice Exam)    
Dec 15 43. Overview - -    
           
Dec 22 Exam IV Friday Evening 5:05 till 7:05 - 125 Ag Hall (covers the whole course)        
           

 

 

  Email Office Voice
John Doebley
jdoebley@wisc.edu
5320 Genetics/Biotechnology 265-5803
Patrick Masson
phmasson@wisc.edu
3262 Genetics/Biotechnology 265-2312

 

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  Last updated October 17, 2006